Galactosyltransferase and Concanavalin A Agglutination of Cells

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Galactosyltransferase and concanavalin A agglutination of cells.

A correlation has been observed between concanavalin A agglutination of various cell types and the presence of surface membrane galactosyltransferase (1-O-alpha-D-Galactosyl-myo-inositol:raffinose galactosyltransferase, EC 2.4.1.67) activity. Moreover, a reduction to less than 50% of cell surface galactosyltransferase activity occurred after treatment with concanavalin A; other cell surface gly...

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Role of cell membrane galactosyltransferase in concanavalin A agglutination of erythrocytes.

It has been previously observed that rabbit erythrocyte cell surface galactosyltransferase appears to play a role in concanavalin A agglutination of these erythrocytes (Podolsky et al., 1974). Further, a correlation between the occurrence or level of cell surface galactosyltransferase and concanavalin A agglutinability of other cell types has also been observed. The mechanism by which rabbit er...

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ژورنال

عنوان ژورنال: Proceedings of the National Academy of Sciences

سال: 1974

ISSN: 0027-8424,1091-6490

DOI: 10.1073/pnas.71.3.904